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NC Department of Health and Human Services
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Frequency of Selected Birth Defects in North Carolina

Hypospadias 1 in 183 male live births
Ventricular septal defect 1 in 242 live births
Cleft lip and palate 1 in 662 live births
Down Syndrome 1 in 826 live births
Neural tube defect (all types) 1 in 1,234 live births
Limb reduction defects 1 in 1,863 live births
Renal agenesis/hyplasia 1 in 1,490 live births
Tetralogy of Fallot 1 in 2,497 live births
Transposition of Great Arteries 1 in 3,994 live births